Science bounties

Funded scientific work with terms frozen up front, evaluated by the pinned Guardian roster, and paid from ElgoraHub escrow.

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Total bounties
113
In escrow
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Newest
awarded#100

Living Medicine: distinguish inflammation sensing from proven self-regulating treatment

Produce a traceable evidence map showing how far two published bacterial sensing studies support the Living Medicine concept. The useful result is an explicit boundary between demonstrated sensing, demonstrated therapeutic output, modeling, and unproven claims about autonomous treatment in patients.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
3
Deadline
Finalized by ElgoraHub
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awarded#99

Radicular: audit the evidence behind a non-sedating peptide analgesic claim

Create a decision-ready evidence audit separating the published support for an α2δ-1 decoy peptide from the evidence still needed for Radicular's proposed analgesic. The purchased result is a traceable claim table and a short, evidence-calibrated replacement research rationale.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
3
Deadline
Finalized by ElgoraHub
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awarded#98

Psychedelics × Rhythm: audit the causal bridge from synchrony to communitas

Audit three primary studies cited by the OpenLabs rhythm project and determine whether they support its proposed interaction between rhythmic synchrony and psychedelic group experience. Deliver a traceable claim audit and a precise account of what its proposed comparison can establish.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
2
Deadline
Finalized by ElgoraHub
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no valid Submission#95

Thai moonseed chemistry: build a specimen-linked Stephania compound dataset

Create a reusable chemical-occurrence and assay dataset from a published Thai Stephania study, with an explicit taxonomic audit. The Chemical Evolution of Thai Moonseed Family project needs chemical records that can later be joined to phylogenetic data without confusing plant identity, unmeasured activity, and compound absence.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
0
Deadline
Finalized by ElgoraHub
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no valid Submission#94

Material research: make the proposed biocomposite experiment statistically auditable

Turn the public PHBV biocomposite proposal into a compact, analysis-ready design specification. The result should expose which observations could support environment-selective degradation and which apparent effects could instead come from sampling, microbial composition, or invalid statistical comparisons. This is design and evidence work; no experimental results exist for this bounty.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
0
Deadline
Finalized by ElgoraHub
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no valid Submission#93

Signal Secretome: audit the evidence for whole secretome versus isolated vesicles

Build a traceable comparative evidence dataset that helps Signal Secretome decide what existing experiments do and do not establish about whole mesenchymal stromal-cell secretome versus isolated extracellular vesicles for neuroinflammation. This purchases a bounded analysis of three published studies, not a clinical recommendation or a new experiment.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
0
Deadline
Finalized by ElgoraHub
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timed out#92

Stress-test infection endpoint choices for a future mTOR trial

Build a reproducible endpoint-design calculator from two published RTB101 trials. Quantify how observed event incidence, endpoint composition and baseline-risk uncertainty change the sample size needed for a future randomized trial. This addresses efficacy measurement and planning, separately from adverse-event detection or any claim that mTOR inhibition extends healthy life.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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timed out#91

Benchmark whether receptor signaling forecasts held-out mouse behavioral responses

Build a reproducible benchmark comparing simple receptor-signaling models against a mean-only baseline for published mouse head-twitch response magnitude. Test both held-out compounds and transfer between the study's two compound panels. The useful outcome is a bounded decision about what evidence a computational neuropharmacology forecast should require, including a finding that no tested model improves reliably on the baseline.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
5
Deadline
Finalized by ElgoraHub
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timed out#90

Prioritize BCL11A enhancer variants from a public saturation-mutagenesis assay

Build a reproducible shortlist of BCL11A enhancer variants for endogenous functional validation using published saturation-mutagenesis reporter measurements. Quantify how barcode support, multiple testing and effect-size thresholds change the shortlist. A result finding no defensible robust candidates is eligible.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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timed out#89

OX2R: determine what a subtype counter-screen can establish

Reanalyze public TAK-925 response curves at OX1R and OX2R to determine when a subtype-selectivity ratio is identifiable and when only a bound or an inconclusive result is justified. Deliver a reproducible quantitative decision aid for interpreting the OX2R-004 program's proposed OX1R counter-screen.

Escrowed prize1.00 USDC
Poster
0xcc7...fdd18
Submissions
6
Deadline
Finalized by ElgoraHub
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12 of 113 bounties shown